Resuscitation, Respiratory Support & Neonatal Care

The AIROPLANE Trial compares two different oxygen concentrations to help support a baby's breathing in the first few minutes after birth. We assess whether either approach leads to babies having less need for later breathing support and oxygen treatment, or spending less time in hospital

This is a randomised control trial comparing different air pressures used for CPAP following extubation of extremely preterm infants (<28 weeks who have received both caffeine and surfactant)

To the determine the ability of point of care lung ultrasound to predict extubation failure in preterm infants born < 32 weeks gestation.

To determine the relationship between lung ultrasound and oxygenation in infants on high frequency oscillatory ventilation who are receiving alveolar recruitment manoeuvres.

To improve neonatal intubation safety via 1) Research- novel research to identify modifiable risk factors in neonatal intubation and test new methods; 2) Education- training providers for intubation safety.

This study aims to develop a new device that gives real time feedback on catheter tip position using the electrical signal from the heart as a guide during and after the insertion procedure.

(In conjunction with Navi Medical Technologies)

Extremely premature babies need help to breathe immediately after birth. This study compares two approaches to supporting their very first breaths.

This study will evaluate the effect of treatment with intravenous pentoxifylline versus placebo, in infants born at less than 29 weeks gestation who have LOS or NEC to see if survival and/or disability is improved.

This study is examining the use of stem cells (given 2 weeks old) to protect the lungs of preterm newborn babies (<29 weeks gestation) with high risk of developing BPD and and evaluating if there is a reduction in the risk of lung disease

This study evaluates the epigenetic changes that are associated with preterm birth and neonatal intensive care

This international trial aims to determine if the breathing outcomes for newborn preterm (less than 28 weeks) babies are improved by giving a combination of steroid & surfactant vs surfactant alone

To assess the effect of blood transfusion with washed compared with unwashed red blood cells on outcomes in extremely preterm infants.