External Collaborations

Harnessing neuroplasticity to improve motor performance in infants with cerebral palsy: a pragmatic randomized controlled trial to determine if enhanced early intervention at a critical phase of brain development improves long term outcome for infants with cerebral palsy

This trial aims to determine if administration of a specific type of stem cell – the human amnion epithelial cell – improves neurodevelopmental outcome and reduces rates of cerebral palsy for infants born extremely premature

To assess the feasibility of:

• targeted salivary cCMV screening at or before 21 days of life, and
• delivering expedited follow up appointments at or before 30 days of life for cCMV positive infants

A multi centre study around Australia examining the use of a new novel screening tool to reduce the age of Cerebral Palsy diagnosis by 6 months through the use of the Baby Moves app in babies born extremely premature and/or with extremely low birth weight

This study collects blood samples to investigate neonatal immunity and coagulation

A randomised control trial to determine the optimal dose of domperidone for the treatment of lactation insufficiency in mothers of preterm infants born less than 30 weeks gestation, with the key objective to determine if administering a higher dose of domperidone (60mg/day) compared to a lower dose (30mg/day) results in a greater increase in daily breast milk supply after 3 weeks treatment

This is an International multicentre randomised control trial to determine whether Epo given in conjunction with hypothermia to infants with moderate-severe hypoxic-ischaemic encephalopathy (HIE) will improve neuro-developmental outcomes at 2 years of age, without significant adverse effects when compared to hypothermia alone.

This multicentre study aims to evaluate the effect of treatment with intravenous Pentoxifylline (PTX) vs placebo, in infants born at less than 29 weeks gestation with Late onset sepsis (LOS) or Necrotizing enterocolisitis (NEC).

This is an International multicentre randomised control trial aiming to determine whether an additional 1 – 2 g/Kg.d protein (amino acid solution [TrophAmine®]) via the UAC starting within 24 hours of birth and continued for 5 days will (i) improve survival free of neurodisability at age 2 years; (ii) improve body composition, and (iii) prevent faltering growth at hospital discharge.

This is a multicentre, randomised control trial to determine whether infants born before 29 weeks and/or less than 1250g birth weight have a better weight at discharge if they smell and taste their milk with every tube feeding compared with routine care (no regular smell and taste exposure)

This study is aiming to determine if babies born> 29 weeks can be supported with medication given directly into the lungs, to avoid the need for ventilation